Kinetics and Mechanism of meso-Tetraphenylporphyrin Iron ..
Mechanism for Synthesis of Tetraphenylporphyrin
In the process, it introduces the CuA center in four different systems---native protein systems, soluble protein truncates of native proteins, synthetic models using organic molecules, and biosynthetic models using proteins as ligands---with a greater emphasis on biosynthetic models of CuA, especially on new, deeper insights gained from their studies.
Mechanism of Acetaminophen Synthesis.
This study provides a methodology for uncoupling covalency from nonlocal electrostatics, which, when coupled to X-ray crystallographic data, distinguishes specific local interactions from more long-range protein/active interactions, while affording further insight into the second-sphere mechanisms available to the protein to tune the E0 of electron-transfer sites in biology.