Major Advance in Artificial Photosynthesis Poses …

Imagine if, based on a complete sequence of your genome, you, the reader, could synthesize your own DNA, introduce it into a human cell and then cause this DNA to take over the command of this cell, forming tissues, organs and even an identical copy of yourself to whom you could transfer your memories.

A potentially game-changing new artificial photosynthesis ..

Synthetic Circuits Powered by Photosynthesis and …

BNL | Chemistry | Artificial Photosynthesis Group

AB - This book provides a systematic and integrated framework to examine key enabling components in the emerging area of synthetic biology. Unique contributions from thought leaders address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. It highlights many exciting examples of practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. In addition, it discusses challenges and future prospects in synthetic biology. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development.

Artificial photosynthesis and carbon capture for producing biofuels

Synthetic Biology emerged in the USA around the beginning of the 21st century. Support for the first version of iGEM, the "International Competitive Student Design of Synthetic Biological Finite State Machines" was awarded in 2003 to bio-, computer- and electrical engineers Drew Endy, Gerald Sussman, and Tom Knight at MIT. It marks an important milestone in what would become a thriving discipline at the intersection of engineering and the biological and physical sciences aimed at applying engineering design principles to understand and harness thehidden potential of biology for making useful products in a sustainable manner. What spawned the field of Synthetic Biology remains debatable; but, it became clear early on that for Synthetic Biology to meet expectations, a convergence of science and engineering disciplines would be essential.

Synthetic biology in industrial biotechnology | …

1998 - marked the first US interagency Metabolic Engineering funding program, a collaboration between NSF, the Departments of Agriculture, Commerce, Defense, Energy, and the National Institutes of Health, that continued until the retirement of its founding program director, Fred Heineken, in 2009. This joint funding program marked the recognition of the importance and economic potential of this field by the relevant US funding agencies. This coordinated funding mechanism leveraged the intellectual perspectives of different agencies, and diminished the duplicate funding of individual efforts, thus increasing the pool of resources to support this precursor to current synthetic biology research.

Synthetic Biology : Tools and Applications

N2 - This book provides a systematic and integrated framework to examine key enabling components in the emerging area of synthetic biology. Unique contributions from thought leaders address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. It highlights many exciting examples of practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. In addition, it discusses challenges and future prospects in synthetic biology. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development.

Nano-Bio Hybrids and Synthetic Biology | Argonne …

2006 - A major boost in the funding of synthetic biology came when teams of leading academic and industrial scientists and engineers in the field were awarded a prestigious NSF Engineering Research Center (ERC) SynBerc[6] the first in the field of bioengineering. The award was in the order of $ 40 Mill. for 10 years. The goal of the center was and is (1) to develop the foundational understanding and technology needed to increase the speed, scale and precision with which to design and build biological solutions; (2) train a new cadre of engineers who will specialize in synthetic biology; and (3) to engage policymakers and the public about the responsible advance of synthetic biology. SynBerc is a multi-institutional consortium with faculty members from UC-Berkeley, Stanford, Harvard, MIT, UCSF, and qb3, as well as a number of industrial firms.