to a method of synthesizing 4-substituted phthalaldehyde

AB - End-capped poly(phthalaldehyde) [PPA] is a well-studied metastable polymer that has attracted interest due to its ease of synthesis and rapid depolymerization. PPA is limited, however, in the type of macromolecular architectures accessible, as functionalizable phthalaldehyde derivatives are not commercially available and their synthesis is cumbersome. To this end, a general route to phthalaldehyde-benzaldehyde copolymers was sought, as benzaldehyde comonomers with various pendant functionalities are readily available. It was found that copolymers are synthesized by an anionic initiated polymerization of phthalaldehyde and electron-deficient benzaldehydes. The comonomer reactivities are shown to be sensitive to the benzaldehyde electronics; the relative reactivity of phthalaldehyde-benzaldehyde comonomer pairs strongly correlate with the Hammett values of the benzaldehyde monomer. These copolymers are then further modified to yield cross-linked, degradable polymer networks in just a two-step sequence. Phthalaldehyde-benzaldehyde copolymers thus enable functionalization of metastable polymers that rapidly depolymerize upon exposure to acid, thereby facilitating the development of triggerable degradation of polymer networks.

Phthalaldehyde : definition of Phthalaldehyde and …

30/01/2004 · Synthesis of 4-substituted phthalaldehyde ..

Study On Synthesis, Of O-phthalaldehyde Disinfectant

Exposure hazards and the potential carcinogenic effects of formaldehyde have limited its healthcare uses recently, while next-generation aldehydes such as glutaraldehyde and o-phthalaldehyde, with better sporicidal activity, faster onset of action and lesser exposure effects, have replaced formaldehyde in the disinfection manuals of most healthcare establishments.

OPA | Ortho-Phthalaldehyde | Showa America | Buy OPA

P-Phthalaldehyds is an intermediate for organic synthesis of pesticides, perfumes, dyes, medicines, plastics, etc., and mainly used in Fluorescent Whitening Agent ER and synthetic plastics.

OPA | Ortho-Phthalaldehyde. Ortho-phthalaldehyde or OPA is a dialdehyde used in the synthesis of heterocyclic compounds and a reagent in the analysis of amino acids.
Substituted o-phthalaldehyde, its production and compound used in synthesis thereof Country Status (5) Country Link;

CANNIZZARO REACTION | MECHANISM | …

Since its introduction in 1999, ortho-phthalaldehyde (OPA) has been accepted as a better, safer alternative to glutaraldehyde in most US healthcare facilities. Cidex OPA by Advanced Sterilization Products (a Johnson & Johnson company) was cleared by the US FDA as a high-level disinfectant and emerged as a suitable replacement of glutaraldehyde for the disinfection of endoscopes.

End-capped poly(phthalaldehyde) [PPA] is a well-studied metastable polymer that has attracted interest due to its ease of synthesis and rapid depolymerization

Infection Control - Centers for Disease Control and …

N2 - End-capped poly(phthalaldehyde) [PPA] is a well-studied metastable polymer that has attracted interest due to its ease of synthesis and rapid depolymerization. PPA is limited, however, in the type of macromolecular architectures accessible, as functionalizable phthalaldehyde derivatives are not commercially available and their synthesis is cumbersome. To this end, a general route to phthalaldehyde-benzaldehyde copolymers was sought, as benzaldehyde comonomers with various pendant functionalities are readily available. It was found that copolymers are synthesized by an anionic initiated polymerization of phthalaldehyde and electron-deficient benzaldehydes. The comonomer reactivities are shown to be sensitive to the benzaldehyde electronics; the relative reactivity of phthalaldehyde-benzaldehyde comonomer pairs strongly correlate with the Hammett values of the benzaldehyde monomer. These copolymers are then further modified to yield cross-linked, degradable polymer networks in just a two-step sequence. Phthalaldehyde-benzaldehyde copolymers thus enable functionalization of metastable polymers that rapidly depolymerize upon exposure to acid, thereby facilitating the development of triggerable degradation of polymer networks.

Definitions of Phthalaldehyde, synonyms, antonyms, derivatives of Phthalaldehyde, analogical dictionary of Phthalaldehyde (English)

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N2 - A novel fluorescent phospholipid, whose structure was tentatively assigned as 1-(2′-thio-1′-hydroxyethyl)-2-(ethylphosphatidyl)isoindole), was synthesized by reacting O-phthalaldehyde and β-mercaptoethanol with phosphatidylethanolamine. The fluorescent lipid product was purified by silicic acid chromatography. The purity was demonstrated by thin-layer chromatography. This fluorescent phospholipid could not form stable lipid vesicles. However, a mixture of phosphatidylcholine and this fluorescent phospholipid did form stable vesicles after sonication, as demonstrated by Sepharose 4B column chromatography and electron microscopy. The absorption and fluorescence properties of this lipid, both as aqueous micelles or incorporated into vesicles, have been determined. The potential usage of this new fluorescent phospholipid in membrane studies is discussed.