Synthesis of Phenyl-2-Propanone (P2P) - …
read Drone #342's Enolate Phenylacetone Synthesis FAQ 1.0.
The closest method is a method of obtaining phenylacetone by reacting phenylacetic acid with acetic acid in the gas is Azay on the catalyst when the temperature of the process 440°With (U.S. Pat. Japan No. 8198796). The initial mixture consists of phenylacetic acid - 2 vol.%, acetic acid - 20 vol.%, nitrogen as the inert - 78 vol.%. The catalyst was a mixture of magnesium oxide with antimony oxide in a ratio of 1:0.1, respectively. The process is conducted with a bulk velocity of the gas stream 4615 h-1The catalyst used in pill form or applied to a carrier of spherical or cylindrical shape. The output of phenylacetone - 68,2%.
Synthesis of Phenyl-2-Propanone (P2P) - Lycaeum
A known method of producing phenylacetone by reacting phenylacetic acid with acetic acid in the gas phase at different catalysts. Thus, in U.S. patent No. 2612524 as catalyst there was used a mixture of magnesium oxide and magnesium hydroxide. In German patent No. 2758113 as the catalyst used zirconium dioxide and thorium dioxide. A common drawback of these methods is primarily low yield is not higher than 61%, in addition dioxide thorium is a radioactive compound.
Phenylacetone | Benchtop Thoughts
The mixture of calcium oxide and magnesium oxide showed higher activity than the catalysts described in the above patents. Method derivatographic was investigated the decomposition generated in the process of acetates. Pure calcium acetate had a decomposition temperature of 430°C. In the presence of minimal amounts of magnesium oxide (1%), its decomposition temperature is reduced to 410°C and the decomposition temperature of magnesium acetate was slightly increased. This proves mutual influence on each other of these two oxides. Lowering the temperature of decomposition of the acetate contributed to the convergence of the temperatures of decomposition of acetate and phenylacetate. Probably, this factor had an effect on the mixed acetate, allowing it is preferable to form phenylacetone relative to the acetone and dibenzalacetone.
Posts about Phenylacetone written ..
This goal is achieved through the use of the method of producing phenylacetone in the gas phase by reacting phenylacetic acid with acetic acid, taken in excess, the catalyst containing a mixture of calcium oxide and magnesium oxide. The process is conducted at a temperature below 350°and the molar ratio of phenylacetic acid to acetic acid 1:(2-5), and the load on the catalyst is 2,2-8,8 kg original mix /(kg cat h). Using the inventive method eliminates the dilution of the mixture with nitrogen.