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The effects of GHB can generally be felt within five to twenty minutes after ingestion. They usually last no more than one and a half to three hours, although they can be indefinitely prolonged through repeated dosing. The effects of GHB are very dose-dependent. Small increases in the amount taken lead to significant intensification of the effect.

What are the effects of stimulants?

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In 'bad trips', pseudo-hallucinations can give way to terrifying true hallucinations, sometimes resulting in very erratic behaviour. In some cases, this psychotic state lasts several days or even longer.

Which depressants are abused?

Many regular users experience unpleasant reactions to LSD sooner or later - or this can happen the first time a person takes the drug. These 'bad trips' can occur anytime with any user. They often take the form of very intense feelings of fear, anxiety or depression. Users may feel that they have lost their identity, their place in the world and that there is no reality to hold on to. It is difficult for anyone who has not experienced this to appreciate just how terrifying it can be - when all perceptions are amplified.

What are the effects of depressants?

* Categories of degree of depression in nontolerant persons:

Although many discos provide 'chill-out' rooms for dancers to cool off in, the availability of such facilities does not make the act of taking ecstasy safe. Some users have died from drinking fluid in excess to combat the overheating caused by ecstasy and made worse by dancing.

2. Sedated, therapeutic range, calm, relaxed, and easily aroused.

Overheating is particularly likely to occur when the drug is taken at a music venue or disco, where the user is dancing. The stimulant effect of ecstasy can enable people to dance vigorously for long periods, leading to exhaustion and heatstroke. When an ecstasy user dances to music with a repetitive rhythm, it seems that the person can 'lock in' to that repetition and simply go though the same movements over and over again for hours. This is a bit like Pavlov's dog - a reflex reaction. It is particularly dangerous as the user may be unaware of impending heatstroke.

Cannabis availability is at an all-time high.

The long-term effects of ecstasy use are not yet known. Ecstasy's chemical cousin, MDA, destroys cells that produce serotonin in the brain. These cells help to regulate aggression, mood, sexual activity, sleep, and sensitivity to pain. Methamphetamine, also similar to Ecstasy, damages brain cells that produce dopamine. It is quite possible that ecstasy can also damage brain cells.

Alcohol is sometimes used as an external local anaesthetic and sterilising agent.

Consequences of amphetamine abuse

The effects of Psilocybe mushrooms are similar to a mild LSD 'trip', that is, they alter the perception of sight, sounds etc. and change the feelings and thoughts of the user. They take effect after about 30-45 minutes, peaking after about 3 hours, and last for around 4 or 5 hours altogether.

Other side effects include blurred vision, sleeplessness, and dizziness.

Nausea, vomiting, constipation.

LSD is commonly known as 'Acid'. It was popular in the UK during the late 1960's and early 1970's and also again in the late 1980's with the rise of 'acid house parties'. Its popularity has declined with the appearance of Ecstasy and LSD now has a relatively limited number of users when compared to that drug.

Many women who use amphetamines find that their periods become irregular or even stop.

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A few ecstasy users have died from brain haemorrhages, which have been caused by the increased blood pressure and heart rate associated with this drug. Some others have died from unknown reasons after taking ecstasy.