Microscale Chemistry - The microscale synthesis of indigo dye
Indigo: History and Synthesis | Dye | Filtration
The product would be made as a paste with an indigo concentration of 20 percent.
The synthesis began with aniline which was reacted with sodium bisulfite and sodium cyanide to form N-cyanomethylaniline.
Baeyer–Drewson indigo synthesis - Wikipedia
A broken thermometer sets the scene for a breakthrough in indigo research. In this example of serendipity at work, BASF scientists discover that mercury is an excellent catalyst in the manufacture of phthalic acid, a key precursor in the synthetic production of indigo. Economic industrial production of the precious blue dye seems a viable option at long last. Seventeen years of research later, it is finally ready for sale as “Indigo rein BASF” (English: Indigo Pure BASF). The synthetic indigo is sold worldwide, especially in China, where blue jackets dyed with indigo are traditional clothing and BASF has been active since 1885. Later, in the 1960s, indigo blue denim jeans are adopted by an entire generation and have become a basic wardrobe essential for many people all over the world today.
German chemist Von Baeyer discovered how to synthesis Indigo.
This review showcases various coupling reagents which have been implemented specifically for large-scale amide synthesis via the condensation of an acid and amine, while highlighting the benefits and drawbacks of each reagent on an industrial scale.
First U.S. Producer of Synthetic Indigo - …
Find out more about this Nobel Prize topic in the new book by Carson J. Bruns, and Nobel Prize winner Sir J. Fraser Stoddart. Read the written by Makoto Fujita and Jean-Pierre Sauvage (2016 Chemistry Nobel Laureate). Read the preface
Many ways exist to prepare the important dye indigo
Ortega-Avilés  detail a variety of other techniques which can be used to determine the composition of a painting, in their case a work titled 'Virgin of Sorrows' (photo, right) which purported to be an 'ancient' piece. Raman and infra-red spectra were taken of the microsamples taken from the painting and the results analysed to determine both the compounds present and specific signatures which betray the origin of the dyes. Specific impurities and methods of binding to canvas fibres help to determine, using data from known samples, where the dyes used came from, when they were made, and which methods were used to extract or synthesise them. The authors found that the painting was elaborated during the middle of the 18th Century or the early third of the 19th Century.