2 Ullmann and Buchwald-Hartwig Diaryl Ether Coupling Reactions

Catalytic Synthesis of Diaryl Ethers with Magnetically Recoverable Fe3O4 Nanoparticles Under Solvent-free and Ligand-free Conditions[J].

2.1 Intermolecular Ullmann Diaryl Ether Coupling Reactions

2.2 Intermolecular Palladium-Catalyzed Diaryl Ether Coupling Reactions
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3 Synthesis of Diaryl Ethers via Nucleophilic Aromatic Substitution

Lett. 5 3799; (c) Cristau H J, Cellier P P, Hamada S, Spindler J F and Taillefer M 2004 A general and mild Ullmann-type synthesis of diaryl ethers Org.

dielectric heating - diaryl ether - diaryl sulfide - synthesis

Chem. 73 7814; (d) Naidu A B, Jaseer E A and Sekar G 2009 General, mild, and intermolecular Ullmann-type synthesis of diaryl and alkyl aryl ethers catalyzed by diol-copper(I) complex J.

2.3 Intramolecular Palladium- and Copper-Mediated Diaryl Ether Coupling Reactions
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Synthesis of diaryl ethers based on one-pot (3 ..

AB - Because diaryl ethers are present as an important motif in pharmaceuticals and natural products, extensive studies for the development of novel methods have been conducted. A conventional method for the construction of the diaryl ether moiety is the intermolecular cross-coupling reaction of aryl halides and phenols with a copper or palladium catalyst. We developed a catalytic decarbonylative etherification of aromatic esters using a palladium or nickel catalyst with our enabling diphosphine ligand to give the corresponding diaryl ethers. The present reaction can be conducted on gram scale in excellent yield. This reaction not only functions in an intramolecular setting but also allows for a cross-etherification using other phenols.

Recent Progress in Diarylether Synthesis[J].

Diaryl ethers form an important class of organic compounds, both in life sciences and in the polymer industry. In general, diaryl ethers can be synthesized by means of copper-catalyzed Ullmann diaryl ether coupling, palladium-catalysed Buchwald-Hartwig reaction, nucleophilic aromatic substitution, arylboronic acid diaryl ether coupling, oxidative coupling, and nucleophilic aromatic addition to metal-arene complexes. This review covers the progress in diaryl ether synthesis since 1999, with literature coverage through September 2005.

Synthesis of Diaryl Ethers: A Long-Standing Problem …

This paper describes the synthesis of diaryl ethers and sulfides by utilizing microwave heating methodology. The methodology is shown to be rapid and efficient for the coupling of phenols or thiophenol with electron-deficient aryl halides through a SNAr reaction. The scope of the protocol can be expanded to six-membered heterocycles bearing a hydroxyl group as well as to the reaction of 2-pyrimidinethiol with mildly activated aryl halides, providing heteroaryl ethers and sulfides, respectively. The advantages of the present method include the wide substrate scope, the obviation of metal catalysts, ease of product isolation, and high purity of products.

Synthesis of aryl ethers - Organic chemistry

Edit. 54 6260; (e) Padalkar V S, Lanke S K, Chemate S B and Sekar N J 2015 N-2-aryl-1,2,3-triazoles: A novel class of blue emitting fluorophores-synthesis, photophysical properties study and DFT computations Fluoresc. 25 985; (f) Obadia M M, Colliat-Dangus G, Debuigne A, Serghei A, Detrembleur C and Drockenmuller E 2015 Poly(vinyl ester 1,2,3-triazolium)s: A new member of the poly(ionic liquid)s family Chem.