The hazards of copper(II) sulfate pentahydrate are described.
Copper(II) sulfate is a compound with the formula CuO 4 S
From the available information on copper(II) sulfate, rats appear to be less susceptible to copper than domestic animals; this pattern is also evident in studies involving repeated exposure (section 7.2).
Copper(II) sulfate pentahydrate is a sulfate salt of copper
In two studies involving the intratracheal instillation in rats of copper(II) oxide (Hirano et al., 1993) or copper(II) sulfate pentahydrate (Hirano et al., 1990) at doses of up to 0.1 or 0.05 mg Cu/rat, respectively (roughly 0.36 or 0.18 mg Cu/kg body weight), acute inflammatory changes were evident in the lungs from 0.018 mg Cu/kg body weight with the soluble sulfate salt and from 0.073 mg Cu/kg body weight with the insoluble oxide.
31/03/2016 · Hoffman, R
When rat hepatocytes were incubated for 20 h with 7.9, 15.7, 31.4 or 78.5 µmol/litre copper(II) sulfate solution (the highest concentration being moderately cytotoxic), there was a significant increase in unscheduled DNA synthesis at each concentration in a roughly dose-related manner.
e-EROS Encyclopedia of Reagents for Organic Synthesis
Copper (II) sulfate, when studied in strains T98, T100 and TA102 of Salmonella typhimurium with and without metabolic activity, even at cytotoxic concentrations or the limit of solubility, did not exhibit mutagenic activity (Moriya et al., 1983; Marzin & Phi, 1985).
Synthesis of Metal-Organic Frameworks (MOFs): Routes …
Exposure to copper(II) sulfate induced effects on neonatal body weight, and on organ weights and biochemistry in mice at 1.3-1.6 mg Cu/kg body weight per day, while higher doses were embryolethal to mice (at 80 mg Cu/kg body weight per day) and to mink (at 12 mg/kg body weight per day).