The following is a list of antibiotics
Types of antibiotics (deprecated - use jsmol version)
Additionally, certain gram negative bacteria have developed specialized enzymatic pumps which actively transport broad ranges of beta-lactams out of the periplasmic space.
Synthesis of β-Lactam Antibiotics: Chemistry, …
Cephamycins have a 7-alpha-methoxy group that gives resistance to beta-lactamases and makes them different from other cephalosporins. Cephamycins are grouped with the second-generation cephalosporins because they have similar activity, with one important exception -- additional activity against gram-negative.
The synthesis of s-methyl and o-methyl β-lactam antibiotics
Without the structural support of cross-linked peptidoglycan, bacteria are sensitive to a variety of environmental stresses that result in lysis of the bacteria; consequently, beta-lactam antibiotics are bactericidal.
The β-lactam antibiotics are ..
This class of antibacterials share a common mechanism of action and a common structural motif known as the "Beta-lactam Ring" which gives the class its namesake.
Beta-lactam Antibiotics | Pathway Medicine
Since 2000 about 20 new antibiotics have been launched, covering five new drug classes for combating bacterial diseases. These five new classes are represented by linezolid (intravenous and oral oxazolidinone, active against Gram-positive cocci, approved 2000), daptomycin (intravenous lipopeptide, active against Gram-positive cocci, approved 2003), retapamulin (topical pleuromutilin, active against Gram-positive cocci, approved 2007), fidaxomicin (oral macrocycle, active against , approved 2010), and bedaquiline (intravenous diarylquinoline, active against , approved 2012). lists new antibiotics approved since the start of the second millennium.
Kinetically controlled synthesis of β-lactam antibiotics ..
More serious but infrequent reactions include: black, tarry stools; painful or difficult urination; antibiotic-induced colitis (severe watery diarrhea, severe stomach cramps, fever, and weakness).