Synthesis and characterization of some metal- vitamin C complexes.
Ofloxacin Metal Complexes: Synthesis, Characterization, Analytical ..
In this review, a summary of the metal complexes which has shown auspicious results has been conversed. Metal complexes proposed a platform for the design of novel therapeutic compounds. The activity of the compound can be increased by the formation of a complex with the different metal ion. It seems that opportunities exist to develop metal and metal-based drug candidates in the discovery and development of novel therapeutic agents. The encouraging results of preclinical and clinical studies with metal compounds form the basis for further investigations towards the development of metal complexes for the better therapeutic profile. Although metal complexes have some side effects, they are successfully being used in cancer therapy and several other therapies. Therefore there is a need for new approaches that are required to circumvent these drawbacks and pave a way for potent drug therapies.
Ofloxacin Metal Complexes: Synthesis, ..
The growth of conflict to anticipated chemotherapeutic drugs shown by some bacteria and fungi has serious insinuations for the sustained success of conventional antibacterial and/or antifungal therapy. However, some transition metal complexes of 1,10–phenanthroline epitomize a novel set of highly active antimicrobial agents whose approach of action is challengingly different to that of the prescription drugs. Hence, by supervisory their selective toxicity or devising appropriate pharmacological properties, they may be used either in combination with existing drugs or where resistance to conservative drugs has emerged.