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The replacement of the specialized species by closely related animals that possessed more flexible adaptations during a time of wide fluctuation in climate was a key piece of initial evidence that led to the variability selection hypothesis. Although Acheulean toolmaking hominins were able to cope with changing habitats throughout much of the Olorgesailie record, the Acheulean way of life disappeared from the region sometime between 500,000 and 300,000 years ago, perhaps also a casualty of strong environmental uncertainty and changing circumstances.

Specific Plaque Hypothesis - Cariology

The ecological concept consolidates both specific and non specific plaque hypothesis theories

Talk:Plaque hypotheses - Wikipedia

As predicted by the variability selection hypothesis, hominins were not found solely in one kind of habitat, but rather in a variety. A major signal of the ability to tolerate different environments was the dispersal of the genus early Homo beyond Africa into Asian environments. After 1.9 million years ago, the genus Homo is found in a variety of locations in Asia, including some that are relatively far north.

Ecological Plaque Hypothesis - Cariology

To summarize, Alzheimer's Disease is a very common case of dementia that has significant implications the future health and well being of elderly patients. Currently, the most accepted hypothesis by scientists is the Beta-amyloid hypothesis which describes possible processing faults involved with the Amyloid Precursor Protein (APP) causing degradation of brain tissue. In most cases, epidemiology shows that age is a main factor for Alzheimer's disease to appear. Characterized by a loss of cognitive function, this debilitating disease unfortunately has no forms of prevention other than eating foods that boost cognitive functions and brain activity. In terms of future research, a novel treatment that has recently been discovered is the use of immunization to stop the development of the disease. Through techniques of active or passive immunization, the administration of antibodies causes alterations and improvement in the beta-amyloid plaques. With such a high onset rate at relatively high ages, future scientific research will be essential to continue to find new preventative measures and more effective treatments.

In the late 20th century a new hypothesis was becoming popular, the specific plaque hypothesis.
non-specific plaque hypothesis: quantity or biomass of dental plaque vs

play an important role in the focal development of atherosclerosis

Over time (from left to right), new adaptations may evolve during periods of (A) relatively stable environment; (B) directional or progressive change, such as from wet to dry; or (C) highly variable habitat, as predicted by the variability selection hypothesis.

No data support the nonspecific plaque hypothesis upon which almost ..


Although the role of aluminum remains controversial, recent research has produced moredefinitive information about zinc, copper & iron — all of which are enriched inamyloid-beta plaques in AD.

Specific Plaque Hypothesis The Specific Plaque Hypothesis attempts to explain the pathological effects of plaque formation in the oral cavity.

Tooth decay, also known as dental ..

Three possible outcomes of population evolution in environmental dynamics typical of the Plio- (left). The ability to move and track habitat change geographically (narrow lines) or to expand the degree of adaptive versatility is important for any lineage to persist. Extinction occurs if species populations have specific dietary/habitat adaptations (i.e., a narrow band of ‘adaptive versatility’; highlighted bands) and cannot relocate to a favored habitat. In the hypothetical situation (right band) where adaptive versatility expands, migration and dispersal may occur independently of the timing and direction of environmental change. The evolution of adaptive versatility is the impetus behind the variability selection idea, which is explored later in this article.