Solid phase peptide synthesis of tri-peptide ..
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Nature makes amide bonds—the key linkages that string together amino acids in a polypeptide—like a knitting whiz. The ribosome in Escherichia coli bacteria, for example, can make eight amide bonds in a second. Chemists are novices by comparison, taking minutes to hours to form an amide bond in a flask. These scientists are stepping it up, though; a group led by Bradley L. Pentelute of MIT has developed a fully automated flow approach to solid-phase peptide synthesis that can make an amide bond in seven seconds and assemble a peptide at a rate of 40 seconds per amino acid (Nat. Chem. Biol. 2017, DOI: 10.1038/nchembio.2318). In solid-phase peptide synthesis, chemists grow a polypeptide chain on a polymer bead one amino acid at a time through cycles of amide-forming reactions. Pentelute and colleagues automated a 2014 manual flow system for such a process, resulting in an apparatus nicknamed “the Amidator.” It
Solid Phase Peptide Synthesis - RealPeptide
Table of spacing values of cobalt and various cobalt oxides to determine the phase of nanocrystallites in and TEM micrograph and SAED pattern of the pure peptide nanowire. This material is available free of charge the Internet at .