(R = Et(OCH2CH2)2)  C6H13NaO3 (MW 156.18)
Sodium Tert.-butoxide - Novasol
Potassium -butoxide in -BuOH or ethereal solvents is not capable of effecting quantitative formation of enolates of unactivated saturated ketones; also, because potassium enolates are subject to rapid proton transfer reactions, their intermolecular alkylations are complicated by equilibration of structurally isomeric enolates, polyalkylation, and aldol condensation reactions. Thus reactions of preformed lithium enolates (generated by deprotonation of ketones with LDA or by indirect procedures) with alkylating agents provide the method of choice for regioselective alkylation of unsymmetrical ketones., However, as illustrated in eqs 3 and 4,, ketones capable of forming only a single enolate, such as symmetrical cyclic ketones and those containing -methylene blocking groups,
Sodium tert-butoxide CAS#: 865-48-5
Sodium tert-butoxide is used as a strong base and a non-nucleophilic base. In organic synthesis, it serves as an intermediate in various reactions like condensation, rearrangement and ring-opening. Further, it finds use in agrochemicals, pharmaceuticals, colorants, aroma chemicals, detergents and biodiesel. It acts as a catalyst in polymerization and isomerization reactions.