sodium potassium atpase | Sigma-Aldrich

The membrane of the neuron is a lipid bilayer with embedded proteins. Some of these proteins are pumps (like the sodium-potassium ATPase pump) but many are ion channels. These ion channels are transmembrane proteins with a complex configuration that includes a pore through which ions can pass. Some channels permit constant passage of ions ("leak channels"), while some are opened by voltage change ("voltage-gated") or by chemical substances ("ligand-gated"). Most channels have selectivity, allowing only certain ions to pass when they are open. This selectivity is due to the particular conformation of the protein or the arrangement of charges in the ion pore.

Search results for sodium potassium atpase at Sigma-Aldrich

Sodium-Potassium-Exchanging ATPase/biosynthesis*

And another example is the hydrogen potassium ATPase ..

To rule out the possibility that apparent stimulation of Na,K-ATPase α2 synthesis stemmed from binding of DHO to Na,K-ATPase sites, experiments were conducted to confirm an increase of Na,K- ATPase α2 polypeptide in the epithelium of lenses exposed to low-potassium medium to inhibit active sodium-potassium transport.

Sodium-Potassium ATPase - an overview | …

Creatine also augments cell volume indirectly. We learned above that the Na+/K+/ ATPase pump uses energy in the form of ATP to move sodium outside the cell, against its concentration gradient. This function is so important for life itself that upwards of 30% of total cellular ATP is used just to keep the Na+/K+ ATPase pump running.

An increase in Na,K-ATPase α2 polypeptide can occur in the epithelium of lenses subjected to an episode of sodium pump inhibition.

Gastric hydrogen potassium ATPase, ..

In the case of ligand-gated ion channel-type receptor, the effect of opening the channel depends on the particular ions that can pass through it. In every case, opening these channels will tend to drive the membrane potential toward the equilibrium potential for the ions to which it is permeable. This has been termed the "reversal potential" for the receptor. If this reversal potential is at a level that would result in the membrane reaching threshold it is termed an excitatory receptor since, if enough of these channels are opened, an action potential will be generated. For example, any ligand-gated receptor that is primarily permeable to sodium or calcium would be excitatory. If the reversal potential for a receptor is at a level that would not reach threshold, it would be an inhibitory receptor. Opening this type of channel would prevent the neuron from reaching threshold and therefore prevent it from generating an action potential. For example, opening a receptor that was permeable to potassium would be inhibitory.

NKAIN2 | sodium/potassium transporting ATPase …

Measurement of net and unidirectional isotopic sodium fluxes, for example during short-circuit conditions, were performed with 22Na and 24Na according to the method of Walser 6. In order to define the site of action of magnesium, experiments were conducted with a protocol in which the driving force of the sodium pump, as well as the conductances of the active transport pathway and the passive shunt pathway, were measured by the method of Siegel & Civan 7 in the presence and absence of magnesium in the mucosal solution,

Thyrotoxic periodic paralysis and polymorphisms of sodium-potassium ATPase ..

Sodium Potassium ATPase Alpha 1 Antibody SKU - …

At this point, you might notice a trend here: as with increased cell volume, amino acid uptake is dependent on sodium, potassium, ATP, and water at the most basic level.

27/06/2011 · Sodium / Potassium Pump - ATPase backwards

1975a, Sodium+potassium-activated ATPase of ..

The extracellular sodium gradient created by the Na+/K+ ATPase pump isn't just important for increased cell volume. Amino acid uptake is also driven by this sodium gradient. To repair trashed muscle tissue, we need to get amino acids inside the cell to turn on protein synthesis. Although all essential amino acids activate protein synthesis to a certain extent, leucine is the most potent trigger.

03/01/2018 · The (Sodium plus Potassium)-Transport ATPase

T3DB: Sodium/potassium-transporting ATPase subunit beta-2

Potassium-selective single membrane channels, inhibited by adenosine triphosphate (ATP), applied to the internal surface of the cell membrane (K+ -ATP channels) have been described in cardiac and muscle cells 29,30 and in insulin-secreting cell 31.