In RNA; role in protein synthesis
Protein Synthesis | Rna | Ribosome
Then, on the inside of the cell, ATP (Adenosine TriPhosphate) binds toanother site on the carrier and phosphorylates (adds one of its phospategroups, or -PO, to) one of theamino acids that is part of the carrier molecule.
(RNA) to facilitate the synthesis of ..
The large subunit then displaces the initiation factors and facilitates the correct alignment of the initiation tRNA on the P site of the ribosome.
From RNA to Protein Synthesis - YouTube
There is another scientific explanation for the origin of life on Earth. It is that whole cells arrived here from space. (Life "in the first place" is a separate issue, dealt with elsewhere on this website.)
Where is the site of RNA synthesis What are homologous ..
Another paper3 describes a method for the inactivation of micro RNA (miRNA) that may help to elucidate their functions. It uses 2’-OMe-RNA oligonucleotides (23-mers, complementary to a target miRNA) with a cholesteryl group at the 3´terminus and phosphorothioates at positions 1 and 2 at the 5´end and at the last four positions at the 3´end. These oligos are called antagomirs. These molecules promote the cleavage of complementary miRNAs and thus should allow analysis of their function. The role of the PS linkages presumably is the stabilization against degradation in the mouse experiments as it is standard in the antisense field in such in vivo situations. And finally, a recent paper4 shows that PS does not systematically abolish siRNA activity, opening the way for some potentially less expensive stabilization of such molecules. Incorporation of 2’-OMe (in the sense strand) in combination with PS linkages should confer to siRNA increased resistance to degradation by nucleases, as well as prolonged serum retention. And it is also possible that such easy modification of siRNA may increase the specificity by eliminating sense strand recruitment in the RISC complex and thus reducing a source of off-target effect.