T1 - Stereoselective synthesis of the C1-C29 part of amphidinol 3

The endocyclic version having distinct geometry are somewhat achievable by way of several protocols, for example, carbonyl olefination, 9 elimination reaction, 10 olefin metathesis, 11 and cycloaddition.

Design, Synthesis, and Antibody Binding Study.

Sonication-Assisted Library Synthesis of Oxazolidinone-Carbohydrate Conjugates.

Synthesis and Application of Glycopeptide and Glycoprotein Mimetics.

In the tradition of the classical Houben-Weyl E21, Stereoselective Synthesis, which covered mainly stoichiometric methods up to the early 90s, the new Stereoselective Synthesis presents the state of the art, including catalytic methods and presenting overviews by experts in the field.

Recent Advances in the Synthesis of Well-Defined Glycopolymers.

Typical or general experimental procedures for the best methods are included.

Stereoselective Synthesis is published in book and electronic form.

Photovoltaic Properties of New Cyanine-Naphthalimide Dyads Synthesized by 'Click' Chemistry.

Synthesis of Lanthanide(III) Chelates by Using 'Click' Chemistry.

Description :Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource p...

Synthesis of Ferrocene-containing Polyacetylenes by Click Chemistry.

N2 - Stereoselective synthesis of the C1-C29 part of amphidinol 3 (AM3) was achieved. The C1-C20 part was assembled from three building blocks via regioselective cross metathesis to form the C4-C5 double bond and addition of an alkenyllithium and a lithium acetylide to two Weinreb amides followed by asymmetric reduction to form the C9-C10 and C14-C15 bonds, respectively. The C21-C29 part was synthesized via successive cross metathesis and oxa-Michael addition sequence to construct the 1,3-diol system at C25 and C27 and Brown asymmetric crotylation to introduce the stereogenic centers at C23 and C24. Coupling of the C1-C20 and C21-C29 parts was achieved by Julia-Kocienski olefination and regio- and stereoselective dihydroxylation of the C20-C21 double bond in the presence of the C4-C5 and C8-C9 double bonds to afford the C1-C29 part of AM3.

Design and Synthesis of Triazole-Based Peptide Dendrimers.

Description :In "Science of Synthesis: Cross Coupling and Heck-Type Reactions", expert authors present and discuss the best and most reliable methods currently available for the formation of new carbon-carbon and ...

Synthesis of a Benzolactone Collection using Click Chemistry.

Annamalai, M.; Hristeva, S.; Bielska, M.; Ortega, R.; Kumar, K. Highly Stereoselective Synthesis of a Compound Collection Based on the Bicyclic Scaffolds of Natural Products. Molecules 2017, 22, 827.

Modular Synthesis of ABC Type Block Copolymers by "Click" Chemistry.

"Stereoselective Synthesis 2" covers stereoselective reactions of carbonyl and imino groups, two of the most integral functional groups employed in organic synthesis.

Synthesis of Triazole-Linked Pseudo-Starch Fragments.

Stereoselective synthesis of the C1-C29 part of amphidinol 3 (AM3) was achieved. The C1-C20 part was assembled from three building blocks via regioselective cross metathesis to form the C4-C5 double bond and addition of an alkenyllithium and a lithium acetylide to two Weinreb amides followed by asymmetric reduction to form the C9-C10 and C14-C15 bonds, respectively. The C21-C29 part was synthesized via successive cross metathesis and oxa-Michael addition sequence to construct the 1,3-diol system at C25 and C27 and Brown asymmetric crotylation to introduce the stereogenic centers at C23 and C24. Coupling of the C1-C20 and C21-C29 parts was achieved by Julia-Kocienski olefination and regio- and stereoselective dihydroxylation of the C20-C21 double bond in the presence of the C4-C5 and C8-C9 double bonds to afford the C1-C29 part of AM3.