Folic Acid Metabolism: A Role in ..
Folic acid plays a critical role in ..
In B12 deficiency, inadequate DNA synthesis seems due in large measure to a block of tetrahydrofolic acid (THFA) regeneration from 5-methyl THFA (via homocysteine transmethylation).
Explain the role of iron,folic acid and Vit
In support of the above, homocysteine appears to facilitate and methionine to reduce de novo DNA synthesis. This was measured by the ability of deoxyuridine to suppress thymidine-3H uptake into DNA in human bone marrow cultures. The homocysteine effect in B12-deficient marrow supports the possibility that there is in man an additional B12-independent pathway for regeneration of THFA by methylation of homocysteine to form methionine.
(remember that folic acid is required for thymine synthesis ..
But genes are not found only in reproductive cells. Every cell in an organism contains DNA (and therefore genes) because DNA also codes for the proteins that the organism produces. And proteins control cell function and provide structure. So, the basis of life happens in each and every cell.
Folic Acid Synthesis Inhibitors - SlideShare
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