- Quora" title="What is an RNA primer and what is its purpose?
- ppt video online download" title="DNA replication 醫技系 楊孔嘉.
During DNA replication, theyfacilitate the untwisting of supertwisted DNA (see also and ).
() proved that DNA replication is semiconservative in
was the first multicellular eukaryotic organism to have its genome sequenced ( Sequencing Consortium, 1998). As sequence information from additional species as well as more distantly-related nematodes has become available in the past decade, the information from has provided the basis for rich comparative genomics studies (). The entire genome is 100 Mb ( Sequencing Consortium, 1998)and has 20,444 protein-coding genes (WormBase release WS245, Oct. 2014). Both sexes contain five autosomal chromosomes named linkage group (LG ) I, II, III, IV, and V and the X chromosome. Individual genes of are arranged in conventional eukaryotic fashion with 5’ untranslated regions, open reading frames (ORFs) containing exons and introns, and 3’ untranslated regions. Compared to vertebrate genes, genes are relatively small with the average gene size of 3 kb due primarily to the presence of very small introns (; genes also have many normal-sized introns). The chromosomes do not contain traditional centromeres; during mitosis the microtubule spindle attaches to more than one position along the chromosome (these attachments are said to be holocentric or polycentric). In fact, a specific sequence does not seem to be required for attachment since extrachromosomal DNA-containing transgenes can be inherited throughout many cell divisions.
The primer acts as the starting point for DNA synthesis.
This enzyme needs the 4 deoxynucleoside 5'-triphosphates, primer DNA, and template DNA and directs the synthesis of a DNA molecule following the sequence of the template strand.