Is Muscle Protein Synthesis the Same as Muscle Growth?
Muscle-building effect of protein beverages for …
It's also clear from the literature that carbs aren't needed to activate protein synthesis after training, but there are other reasons to include carbs, which we'll get into later.
state exercise enhances postexercise muscle protein synthesis.
Several studies have shown mTOR activation by leucine intake directly after resistance exercise. One study by Walker et al.1 showed that leucine consumption shortly after working out increased mTOR activity for several hours post-workout, leading to greater muscle protein synthesis as compared to an exercised group that was not fed leucine. A second investigation by Pasiakos et al.2 demonstrated that consumption of leucine immediately after exercise increased muscle protein synthesis by as much as 33 percent.
At the same time as leucine consumption enhances muscle protein synthesis after resistance training, it also decreases muscle protein breakdown during and following exercise by activating mTOR 3, which turns off the enzyme AMPK.4 AMPK [AMP-activated protein kinase] is the muscle cell’s energy gauge that promotes the breakdown of protein into amino acids when muscle cell energy is low, so the amino acids can be used for energy to restore the cell’s energy status. Therefore, leucine consumption during and after prevents the AMPK-driven breakdown of lean body mass, which enhances the hypertrophic response of muscle tissue.