1. To introduce basic concepts of organic synthesis:

Reactions are usually straightforward (SEAr) and you will have met most of them before. Synthesis is simplified because the nature of the starting materials is usually clear. Thus, most reactions correspond to the following disconnection:

Also in CCBFR, organometallic compounds are important.

3. To illustrate the importance of organic synthesis with real examples.

Also in CCBFR, organometallic compounds are important.

focuses on molecular recognition events that proceed through hydrogen-bonding since they often provide the molecular "Velcro" to organize molecules in well-defined chemical environments and the proton source required for catalysis by enzymes. Critical to life processes, our primary research interest involves understanding the molecular recognition event of biological ions via hydrogen bonding by understanding the thermodynamic role conformation and solvation factor on these events. Future studies of these projects will include the ability of our receptors to chaperone ions into cell membranes and to orient molecular ions into well-defined orientations so that they can be used as a chiral, preorganizing unit to conduct reactions with high selectivity.

T1 - Solid-phase organic synthesis of heterocyclic compounds

focuses on preparing organometallic or transition metal complexes which exhibit catalytic activities. For instance, they prepared some small Fe complexes which mimic the function of Methane Monooxygenase (MMO) by showing highly catalytic activity of C-H oxidation. They identified the key structure required and characterized them by a variety of spectroscopic techniques, magnetic measurements, and X-ray crystallography.


Grignard Synthesis of Methamphetamine ..

Reactions are usually straightforward (SEAr) and you will have met most of them before. Synthesis is simplified because the nature of the starting materials is usually clear. Thus, most reactions correspond to the following disconnection:

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studies the mechanism based development of new methods and reagents for the synthesis of fine chemical and pharmacological organic molecules. Target molecular systems include nitrogen and oxygen heterocycles possessing chirality. Our synthetic methods work places a premium on developing economically and environmentally responsible chemistries. Our current studies utilize microwave and organocatalytic methods and are focused on developing asymmetric routes to dihydropyridazines and dihydrophthalazinones and the development of new low cost reagents for the synthesis of carbohydrate and pseudo-carbohydrate targets.

Organic Synthesis and Carbon-Carbon Bond Forming Reactions

synthesizes ligand-capped metal nanoparticles that are active catalysts for regio-, chemo-, and/or stereo-selective organic reactions, with a strong emphasis on controlling the structure and functionality of surrounding thiolate ligands. Recently, our group discovered a synthetic method to generate stable and isolable Pd nanoparticles capped with a low density of alkanethiolate ligands. The Pd nanoparticles synthesized using Bunte salts as a source of protecting ligands exhibit a high selectivity for isomerization of allyl alcohols to the corresponding carbonyl compounds. With further efforts in controlling the size and/or composition of nanoparticle core (Au, Ag, Pt, and Ir) and the structure and/or functionality of surrounding ligands, the catalytic activity and selectivity of metal nanoparticles can be further optimized for many reactions including the isomerization/hydrogenation of unsaturated alcohols, alkenes, alkynes, and carbonyls and the reduction of unsaturated nitrogen-containing compounds. The produced ligand-capped metal nanoparticles can also serve as a stable model "micellar" and/or "metalloenzyme" system with an active catalytic center in aqueous environment.

and are the core of mechanochemical organic synthesis

– a paper operation involving an imagined cleavage of a bond (yielding ‘synthons’) to suggest a method and possible SM’s for making the bond, ultimately leading to possible SM’s for the overall synthesis.

Modern Methods of Organic Synthesis eBook: W. …

– a paper operation involving an imagined cleavage of a bond (yielding ‘synthons’) to suggest a method and possible SM’s for making the bond, ultimately leading to possible SM’s for the overall synthesis.