The 14-3-3 proteins: cellular regulators of plant metabolism.

Para-aminophenol produces acute necrosis of the proximal convoluted tubules in rats after a single injection (Green et al., 1969), and has been demonstrated to be a minor metabolite of paracetamol in the Fischer-344 rat and its isolated perfused kidney (Newton et al., 1982).

Genetic variability of proteome expression and metabolic control.

Aspergillus NDPK consists of 154 amino acids with 65% sequence identity to human Nm23.

On the free amino acids in anthers of male-sterile wheat and maize.

Experimental approaches using different species and strains of animals, inducers and inhibitors of drug metabolizing enzymes, and candidate proximate and ultimate nephrotoxic metabolites may give some evidence for the involvement of intrarenal metabolic activation (Rush et al., 1984).

Vitamin E biosynthesis: biochemistry meets cell biology.

The sclerotia contain a large number of biologically active alkaloids, as well as amino acids, carbohydrates, lipids, and pigments, and, when the sclerotia are consumed by man and animals, toxicosis develops, called ergotism.

Sugar starvation induced changes of carbon metabolism in excised maize root tips.

Chemical Regulation of Mycotoxin Biosynthesis

Mice (male, Swiss strain weighing 25 g) received inoculations (route not stated) of Cryptococcus neoformans (1 x 106 cells) and ip doses (1/8 or 1/4 LD50) of DAS on days 5, 6, and 7 after inoculation with the fungal cells.

polyols to the regulation of mycotoxin biosynthesis in F ..

The reversible binding of a metabolite of 2,2,4trimethylpentane to alpha2u-globulin in the male rat kidney (Lock et al., 1987) is thought to alter endocytosis or lysosomal handling of the alpha2u-globulin-2,2,4-trimethylpentane metabolite complex.

Metabolic regulation of mycotoxin biosynthesis

T-2 toxin (0.5 mg/kg body weight) dissolved in 1:1 mixture of propylene glycol and 0.1N sodium bicarbonate was administered ip alone or in combination with rubratoxin B (0.4 mg/kg body weight) to pregnant CD-1 mice on day 1 of gestation.

The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase.

(1972b) Renal contribution to overall metabolism of drugs.

There is now substantial evidence that hepatic and renal tissue respond differently, both quantitatively and qualitatively, to the various inducers of cytochrome P-450 (Litterst et al., 1977; Zenser et al., 1978a; Kaminsky et al., 1979).

Multiple doses (8-12 or 8-14 days of gestation) of 1.0 or 1.6 mg/kg produced 100% abortion.

Regulation of Mycotoxin Biosynthesis - UNIV OF …



The term “specialized metabolism” encompasses metabolic processes that are asymmetrically distributed across phylogenetic space - historically this metabolism was called secondary metabolism. In contrast to central metabolism, which is common to all life forms, specialized metabolism generates the “chemical-spice” of different life forms, and thus is responsible for the large degree of chemical diversity in the biosphere.

Physiology of maize I: A comprehensive and integrated view of nitrogen metabolism in a C4 plant.

REGULATION OF ASPERGILLUS MYCOTOXIN BIOSYNTHESIS…

The disturbances in calcium and phosphorus metabolism may lead to a demineralization of the bones and the formation of kidney stones (Friberg et al., 1974).