Synthesis of Thyroid Hormone
Human Growth Hormone - Encyclopedia Britannica
Only few investigations pertained hepaticexpression of IGFs and their receptors at different stages ofchronic hepatitis C in humans (). The studies demonstrated anincreased IGF-1R mRNA, but not IGF-1 protein in patients with CHCas compared to the control (). HCV replication was associatedwith the overexpression of IGF-2 in the cirrhotic livers (). Studies on HCV-related HCCsdocumented increased expression of IGF-2 in 50% of HCCs. Theincreased synthesis of IGF-2 (mRNA and protein) was associated withan increased cellular proliferation in HCCs (). The results observed in tissuesamples suggest that IGF-2 might be responsible for IGF-1Ractivation ().
Recombinant Human Growth Hormone (GH) Protein …
In all studied tissues of HCC (n=28) a decreasedexpression of IGF-1 and IGF BP-3 and in 32% of them an increasedexpression of IGF-2 was detected (). Decreased amounts of IGF-1 mRNA() or both IGF’s mRNA (–) in HCCs were demonstrated ascompared to the control. In case of IGF-1 transcript, the decreasewas more pronounced than that in IGF-2 (–). In hepatocarcinogenesis in ratsappearance of IGF-2 mRNA was demonstrated upon a decrease in IGF-1mRNA (). An increasedexpression of IGF-2 (protein and mRNA) was demonstrated inHBV-related HCC (). IGF-1,IGF-2 and IR mRNAs were detected at various stages of HCCdevelopment and in cultured cells. The studies showed that isolatedhepatocytes synthetise IGF-2 mRNA with a switch between fetal andadult mRNA profiles occurring 21 days after birth ().
Somatropin - Human Growth Hormone
TOTAL DAILY (1MG=2.7 I.U)
WATER RETENTION: VERY RARE
HIGH BLOOD PRESSURE: VERY RARE
LIVER TOXIC: NONE
HIGH ANABOLIC/NO ANDROGENIC EFFECTS
HUMAN GROWTH HORMONE (GH) HAS BEEN A SUBJECT OF DEBATE SINCE I WAS A KID.
Human growth hormone is very dangerous ..
However, it is very essential to understand, that even a “miracle” chemical like Human Growth Hormones comes along with set of pros and cons. Thus, if taken when it is very needful, it works at best. Few side-effects may be joint pains, breast tissue enlargement in men, swelling and pains in ankles and feet, hormonal disturbance. Especially, if a woman is pregnant, nursing mother or is under any pregnancy treatment, this pill should be avoided. Although, it has been approved by FDA (Food and Drug Administration), their risks still prevail. Hence, one should be cautious about its intake and should be taken under physician supervision only.