High-density lipoprotein - Wikipedia

The promotion of atherosclerosis regression by high-density lipoprotein (HDL) in an aortic transplantation mouse model. Monocytes are recruited into plaques and become macrophages. These macrophages become activated, cholesterol-laden foam cells, as a result of ingesting normal and modified apolipoprotein B–containing lipoproteins and are retained in the plaque. On the basis of in vitro and preclinical studies, we found that the recently recognized ways in which HDL can contribute to plaque regression include reduced monocyte recruitment because of reduced leukocytosis or endothelial cell adhesion molecule expression, the stimulation of C-C chemokine receptor type 7 (CCR7) expression by the promotion of cholesterol efflux from foam cells, which results in emigration of macrophages to lymphoid tissue and to the systemic circulation, and the stimulation of the STAT6 pathway to polarize macrophages to the M2 state, as indicated by the increase in the markers mannose receptor (MR), interleukin (IL)-10, and arginase I (Arg I). As tissue repairs cells, M2 macrophages also exhibit enhanced efferocytosis (disposal) of apoptotic cells. See text for details and for additional mechanisms. LDL indicates low-density lipoprotein. []

Low-density lipoprotein - Wikipedia

High-density lipoprotein and coronary heart-disease: a prospective case-control study

(IDL), low-density lipoprotein and high-density lipoprotein ..

To assess the feasibility of recombinant high density lipoprotein (rHDL) reconstituted with apoA-V and apolipoprotein A-I (apoA-I) as a therapeutic agent for hyperlipidemic disorder and atherosclerosis, a series of rHDL were synthesized in vitro with various mass ratios of recombinant apoA-I and apoA-V.

High-density lipoprotein synthesis and metabolism …

It is interesting to find that apoA-V of rHDL had no effect on lipoprotein lipase (LPL) activation in vitro and very low density lipoprotein (VLDL) clearance in HepG2 cells and in vivo .

(1982) High -Density Lipoproteins and Atherogenesis, in Lipid Metabolism and Atherosclerosis (Assmann,G., eds), pp81-100,Schattauer, Germany

Low total, low-density lipoprotein, high-density lipoprotein, ..

Pagler TA, Rhode S, Neuhofer A, Laggner H,et al: SR-BI-mediated high density lipoprotein (HDL)endocytosisleads to HDL resecretion facilitatingcholesterol efflux. J BiolChem. 281:11193–11204. 2006. : :

High density lipoprotein receptors, binding proteins, …

Brundert M, Ewert A, Heeren J, Behrendt B,Ramakrishnan R, Greten H, Merkel M and Rinninger F: Scavengerreceptor class B type I mediates the selective uptake ofhigh-density lipoprotein-associated cholesteryl ester by the liverin mice. Arterioscler Thromb Vasc Biol. 25:143–148. 2005.

05/12/2017 · One is low-density lipoprotein, ..

Vaughan AM and Oram JF: ABCG1redistributes cell cholesterol to domains removable by high densitylipoprotein but not by lipid-depleted apolipoproteins. J Biol Chem.280:30150–30157. 2005. : :

Landmesser U: High density lipoprotein –should we raise it? Curr Vasc Pharmacol. 10:718–719. 2012. :  :

What is a high-density lipoprotein (HDL)

Terasaka N, Wang N, Yvan-Charvet L andTall AR: High-density lipoprotein protects macrophages fromoxidized low-density lipo-protein-induced apoptosis by promotingefflux of 7-ketocholesterol via ABCG1. Proc Natl Acad Sci USA.104:15093–15098. 2007. :

Rye KA: Biomarkers associated withhigh-density lipoproteins in atherosclerotic kidney disease. ClinExp Nephrol. 18:247–250. 2014.  :

4) High Density Lipoprotein (HDL) - Willy Organic Chemistry

Tall AR: Plasma cholesteryl ester transferprotein and high-density lipoproteins: New insights from moleculargenetic studies. J Intern Med. 237:5–12. 1995. : :

(1992) High-density Lipoproteins, in Plasma Lipoproteins and Coronary Artery Disease (Kreisberg,R.A.

High Density Lipoprotein (HDL) Promotes Glucose …

Fisher EA, Feig JE, Hewing B, Hazen SL andSmith JD: High-density lipoprotein function, dysfunction, andreverse cholesterol transport. Arterioscler Thromb Vasc Biol.32:2813–2820. 2012. : :