Seroprevalence of HBV markers in Northeast China by age groups

The national expanded program on immunization was instituted in China in 1992. As of December 2007, 171 counties reported that they had included the hepatitis B vaccine into their national infant immunization programs []. In China, babies are given the hepatitis B vaccine at birth. The national infant immunization program focuses on blocking mother-to-child transmission of hepatitis B. The vaccination program has produced encouraging initial results in China. The prevalence of HBsAg was 0.96% and 2.42% in children aged 1—4 and 5—14, respectively [-]. In addition to infant immunization, some adult members of China's population have been vaccinated voluntarily, outside national vaccination programs. However, older age groups, especially adults, have not received sufficient attention. Despite the availability of safe and effective HBV vaccines for over 20 years, strategies targeting risk groups have failed to sufficiently control hepatitis B transmission in the current population. HBV transmission has become an important mode of infection in adults, mainly because of difficulties in risk identification and in program implementation. Therefore, we conducted this study to determine the prevalence of HBV infection and the major independent risk factors for HBV transmission in an adult population in northeast China.

Update on Prevalence, Diagnosis, and Treatment of HBV (PPT Thesis) 1

The majority of people do not have noticeable symptoms when they are first infected with the HBV.

the prevalence of HBV infection in Nigeria in ..

On multivariate analysis, seroprevalence of HBV remained negatively associated with personal history of vaccination and age. People in the 18-29 age group had a greater likelihood of having been infected by hepatitis B [HBsAg(+)], and a negative trend was seen with age. In contrast, a positive association was present with smoking, bad sleep quality, being a peasant, laborer, or private small-businessman, family history of HBV, or male (Table , Fig.).

Update on prevalence, diagnosis, and treatment of hbv (thesis)

Professor and Director General
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DUANQING PEI PhD is Professor of stem cell biology and also serves as the Director General (President) at the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, in Guangzhou, China. He obtained his PhD from the University of Pennsylvania in 1991 and trained as a postdoctoral fellow at the University of Michigan before becoming a faculty member at the University of Minnesota School of Medicine in 1996. He joined the Medical Faculty at Tsinghua University in Beijing China in 2002 and moved to the newly formed GIBH in 2004.

Dr. Pei studied the transcription regulation of hepatitis B virus (HBV) for his Ph.D. thesis by identifying C/EBP as a repressor for HBV transcription and dissecting the transactivation domains in C/EBP. Then he shifted his research interest into the field of extracellular matrix remodeling by studying the structure and function of matrix metalloproteinases (MMPs). He cloned several novel members of the MMP family, uncovered the unique intracellular activation mechanism of MMPs with the proprotein convertase system, and the intracellular trafficking of membrane-bound MMPs. Upon returning to China, he once again changed his field of study and started working on pluripotency first and then reprogramming. The Pei lab in Tsinghua began to publish in the stem cell field on the structure and function of Oct4, Sox2, FoxD3, Essrb, and Nanog, and their interdependent relationship towards pluripotency. Based the understanding of these factors, the Pei lab was the first in China to create mouse iPSCs using a non-selective system, and then improved the iPS process systematically. The Pei lab subsequently disseminated the iPS technology in China by providing not only resources, but also training workshops. Recent publications from the Pei lab includes the discovery of vitamin C as a potent booster for iPSC generation and a mesenchymal to epithelial transition initiates the reprogramming process of mouse fibroblasts. Now, his lab continues to explore new ways to improve iPS technology, dissect the reprogramming mechanisms driven by Oct4/Sox2/Klf4 or fewer factors, and employ iPSCs to model human diseases in vitro.

People who do not know they are infected with the HBV, their body can respond in different ways....
The genome of HBV is circular, partly double stranded, and approximately 3,200 nucleotides long.

trends in the prevalence of hepatitis B virus (HBV) ..

Liver disease, particularly in the post antiretroviral era of HIV/AIDS, has emerged as a major cause of morbidity and mortality in Hepatitis B (HBV) or Hepatitis C (HCV) co-infected patients 1-4.

Prevalence of HBV Markers According to Sociodemographic Variables in the Jilin, China (n=3833)

HKU Li Ka Shing Faculty of Medicine

Due to its prevalence among such already marginalized members of society, hepatitis B was viewed as a highly stigmatized disease and further research concerning HBV was not a top priority in the United States....

To facilitate thepenetration and internalization of HBV, the expression of annexin V (A V) was

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In the end, 3833 people agreed to participate in the study, and their serum samples, demographic information, and behavioral factors were collected. The response rate was high (95.8%, 3833/4000). When we analyzed the relationship between HBV markers and liver enzymes, we excluded 75 people who had abnormal autoantibodies, ceruloplasmin, and iron tests. They consisted of 30, 29, 16 people, respectively. In addition, 98 people were excluded who reported consuming at least 40 g of alcohol per day, and 45 hepatitis C virus (HCV)-positive people were excluded in the analysis of the relationship between HBV markers and liver enzymes.