GeneExpression and Protein Synthesis
DNA is transcribed into RNA, which istranslated into protein.
c)Forall three polymerases, the TATA‑binding protein is a subunit of atranscription factor required for initiation (not necessarily the same factorfor each polymerase).
The site of protein synthesis is
RNApolymerase II, the GTFs, SRB proteins and other regulatory proteins have nowbeen shown to interact in large complexes in the nucleus (Table 3.1.6). Acomplex called the mediator transcription of DNA using purified RNApolymerase II and GTFs failed to increase the amount of transcription whentranscriptional activators were added. However, a component in nuclear extractswould confer the ability to respond; this was called the mediator ofactivation. When purified, it was discovered to contain several Srb proteins,Gal11, Rgr1 and other transcriptional regulators.
Protein Synthesis - Estrella Mountain Community College
In prokaryotes mRNA is translated as it is being transcribed from DNA
In eukaryotes it has to be transported to the cytoplasm before translation
In prokaryotes the mRNA is used immediately but in eukaryotesit must be modified before it leaves the nucleus
Protein synthesis is also much faster in prokaryotes.
The Genetic Code: Translation of RNA code into protein | Back to Top
Ribosomes, Protein Synthesis and the Genetic Code
Free ribosomes are in the cytosol
Bound ribosomes started in the cytosol but attached to the endoplasmic reticulum.
Protein Synthesis - MCAT Review
A stop codon is recognized and release factors stop translation
Instead of an amino acid, water is added
The new protein, mRNA and tRNA are released and the ribosome dissociates.
Polyribosomes or polysomes are ribosomes that can translate a single mRNA simulataneously
This creates many copies in very little time
After translation the protein must fold into a 3D shape before it is functional.