Efficient microwave-assisted synthesis of bisimides - …
Fast and Efficient Microwave-Assisted Synthesis of ..
The conjugation of ILs and microwave irradiation as a non-conventional heating source has shown evident advantages when compared to conventional synthetic procedures for the generation of fast, efficient, and environmental friendly synthetic methodologies.
“Microwave assisted synthesis of imides and bisimides”
Microwave dielectric heating proved to be an efficient method for the one-pot and stepwise syntheses of symmetrical and unsymmetrical naphthalenediimide derivatives of α-amino acids. Acid-labile side chain protecting groups are stable under the reaction conditions; protection of the α-carboxylic group is not required. The stepwise condensation of different amino acids resulted in high yields of unsymmetrical naphthalenediimides. The reaction proceeds without racemization and is essentially quantitative.