dna replication and protein synthesis Flashcards | Quizlet
DNA, RNA and Protein Synthesis Flashcards | Quizlet
can produce enough RNA to make thousands of copies of the same protein in a very short.
Processing of Gene Information - Prokaryotes versus Eukaryotes (663.0K) Protein Synthesis (1011.0K) How Spliceosomes Process RNA (617.0K).
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resulting in the production of unique proteins that perform numerous and specific functions.
DNA and Protein Synthesis - BioTopics Website
In prokaryotes RNA processing is not necessary, but in eukaryotes the RNA must be processed before translation can occur.
3 main steps:
capping at 5' end
RNA splicing to remove introns
addition of polyA tail
Primary transcript is the initial product of transcription of an mRNA
Most genes have their protein-coding information interrupted by non coding sequences called
The 5' end of the primary transcript (pre-mRNA) is synthesized first.
The 5' cap is a modified guanine nucleotide which attaches to the 5-end of the pre-mRNA.
The cap protects the RNA from being degraded by enzymes that degrade RNA at the 5' end.
RNA splicing removes introns and exons are joined.
exons are a sequence within a primary transcript that remains in the RNA after RNA processing.
RNA splicing begins with helper proteins at intron/exon borders, defining the DNA that will be cut out.
Small nuclear ribonucleo proteins (snRNPs) recognize the splice sites.
A spliceosome is made up of proteins and RNA molecules that splices RNA by interacting with the ends of an RNA intron, releasing the intron and joining the two adjacent exons.
Synthesis of Poly-A tail
Poly-A tail is a stretch of adenine (A) nucleotides.
When a special poly-A attachment site in the pre-mRNA emerges, the transcript is cut there and the poly-A tail is attached to the exposed 3'end.
This completes the mRNA molecule which is ready to be transported to the cytoplasm.