Our custom DNA portfolio features
Biolegio | Custom Oligos Synthesis
As the largest gene synthesis provider, we provides standard oligos and custom modified DNA oligos with comprehensive modifications and labeling to meet research needs in biology, diagnostics, and drug discovery.
e-oligos: Premium Custom Oligo Synthesis
Your research will benefit from our 35 years as the leader in DNA, RNA, and LNA oligonucleotide synthesis. MCRC pioneered the use of MALDI-TOF mass spectrometry as a quality assurance measure; a technique that has become the gold standard for the industry. We remain committed today to providing the highest quality products researchers around the globe.
DNA RNA Oligo Synthesizer - Dr ..
With over 20 years of experience in oligo synthesis, Metabion can provide you with a full range of DNA oligonucleotides and modifications of highest quality at competitive prices!
Custom Services for oligonucleotide synthesis ..
RNA oligos are susceptible to degradation to the same extent as native RNAextracted from various sources. An attractive alternate to prevent degradationfrom nucleases is the use of 2-O- methyl RNA bases, when specific 2OH isnot required. The 2-O- methyl oligonucleotides confer considerable nucleaseresistance and are similar in hydrogen bonding properties to RNA/RNA than thelower RNA/DNA binding property. The coupling efficiency of 2-O- methylphosphoramidite is also higher than the RNA monomers resulting in higher yieldof full length oligos.
Custom Oligo Synthesis - General Biosystems
Oligos are made using a DNA synthesizer, which is basically a computer-controlled reagent delivery system. The first base is attached to a solid support, usually a glass or polystyrene bead, which is designed to anchor the growing DNA chain in the reaction column. DNA synthesis consists of a series of chemical reactions.