Synthesis of cephalosporin-4-aldehydes.
Synthesis and chemistry of cephalosporin ..
This week’s group meeting’s talk on ‘Strategies in Synthetic Planning’ raised a number of interesting points for discussion, but I wanted to put just one to my readers and the online synthetic community: what’s your favourite total synthesis?
SYNTHESIS AND CHEMISTRY OF CEPHALOSPORIN SULFENATE ESTERS E ..
Paul Dochety's blog at was a massive inspiration to me in my early days as a blogger, showing me that there was enough of a synthetic organic chemistry community online to make writing seemingly very esoteric posts on a small, specialised sub-field rewarding and worthwhile. A couple of years ago, Paul moved away from the online community, but continued his excellent monthly column for the RSC's (think British C&EN, if you're not familiar with it). However, his tenure there has recently also , and to try to fill the organic-shaped hole in its opinion pages the RSC has commisioned a new column – Organic Matter. As you've probably , authorship will be shared between myself, Karl Collins (of ) and the legendary Chemjobber (anyone who needs a should really rethink their blog-reading priorities).
Synthesis of a cephalosporin-doxorubicin antitumor ..
Given the massive number of people affected worldwide by neurodegenerative diseases and nerve injuries, it's not surprising that a number of synthetic groups have chosen to focus their research programs on neurotrophic natural products. Of course, it's probably coincidence that aside from their potential uses to society, a number of these compounds seem to also be structurally unique and strikingly intricate molecules. One such example is jiadifenolide, whose dense, caged seco-prezizaane-type structure has already seen 3 total syntheses since its isolation five years ago.
Synthesis Of Dipeptide Linked-cephalosporins To …
In the four months I spent not writing this post, the Paterson–Dalby synthesis of jiadifenolide was , but as I’d already put a few hours into it I decided to use the Christmas holidays to dust it off and finish it up. Enjoy! —BRSM