Synthesis of artesunate with different stoichiometric ..

Professor Young-Joon Surh is currently Director of Tumor Microenvironment Global Core Research Center, Seoul National University, Korea. He graduated from College of Pharmacy, Seoul National University with BS and MS, and earned a PhD degree at the University of Wisconsin-Madison. Professor Surh then had postdoctoral training at the Massachusetts Institute of Technology. In 1992, he was appointed as Assistant Professor at Yale University School of Medicine. Since relocating to Seoul National University in 1996, Dr. Surh has been investigating the molecular mechanisms of cancer prevention with anti-inflammatory phytochemicals. He is currently Associate Editor of Molecular Carcinogenesis, Toxicology & Applied Pharmacology, and Free Radical Research, and Editorial Board member of Antioxidants & Redox Signaling, International Journal of Cancer, Mutation Research, Life Sciences, Food and Chemical Toxicology, Genes and Nutrition, Molecular Nutrition and Food Research, and more recently Precision Oncology published by Nature Publishing Group. Prof. Surh has published more than 280 papers in peer-reviewed international journals and about 70 invited editorials, reviews and book chapters. The total number of citations of his publications is more than 17,000 (excluding self-citations). He published a seminal review article, titled cancer chemoprevention with dietary phytochemicals, in Nature Reviews Cancer which has been cited more than 1,600 times. The H-Index reported by Thomson Reuter of Web Knowledge is 68. He received numerous awards including Elizabeth and James A. Miller Distinguished Scholar Award from Rutgers University, McCormic Science Institute Award from American Society for Nutrition (2009), and the Distinguished Scientist Award given by President of South Korea.

Sanofi’s API produced from semisynthetic artemisinin (artesunate) ..

02/12/2016 · A simplified and scalable synthesis of artesunate
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Because the chemical synthesis of ..

Dr Denis Barron is the head of the Natural Bioactives & Screening department at Nestlé Institute of Health Sciences (NIHS), Lausanne, Switzerland. He first studied Pharmacy at the Universities of Clermont-Ferrand and Grenoble. He obtained his PhD in 1987 from Concordia University (Montreal, Canada), where he worked on the phytochemical characterization, the chemical synthesis and the enzymatic synthesis of plant sulfated flavonoid. Then he entered the French institute of Agriculture (INRA) in Dijon as a research assistant in the field of aroma research. In 1989, he got an assistant professorship in Pharmacognosy at the school of Pharmacy of Grenoble (France), and developed a number of synthetic tools for the organic synthesis of isoprenoid flavonoids. In 1994, he was nominated full professor in plant biochemistry at University of Lyon (France). His research interest was oriented towards the discovery of natural inhibitors of cellular efflux pumps that are involved in chemoresistance and nutrient absorption such as P-glycoprotein and MRP. Dr Barron research activities, at the boarder of pharmacy and nutrition, gave him the opportunity to join Nestlé Research Center (NRC) in Lausanne in 2003. At NRC his research activities were oriented towards the human metabolism of dietary polyphenols, and towards the characterization of bioactive compounds from food ingredients. In 2012, he moved to NIHS. His current activities aim at identifying natural food products and extracts that are relevant in the prevention and the treatment of metabolic, brain, and gastro intestinal diseases.

Artesunate (AS) is a medication used to treat malaria

Professor Dr. Prof. h. c. mult. Thomas Efferth is chair of the Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Mainz, Germany. He is biologist by training (Technical University of Darmstadt, Germany). His doctoral thesis was completed at the German Cancer Research Center (DKFZ), Heidelberg, Germany (1990). Dr. Efferth was awarded the Ludolf-Krehl-Prize of the Southwest German Association for Medicine (1991), the Willmar-Schwabe-Award of the German Society for Medicinal Plant Research (2006), the citizen medal of the City of Heidelberg, Germany (2008), the CESAR Award for Translational Oncology (2011), and the SCENTEDdrop Award on medicinal and flagrant herbs (2015). He headed a research group for Pharmaceutical Biology at DKFZ (2005-2009) and was associate professor (apl) at the University of Heidelberg (2007-2009). In 2009, he took over the Chair of Pharmaceutical Biology (full professorship) at the Johannes Gutenberg University, Mainz. Furthermore, he is honorary professor at the Northeast Forestry University, Harbin, and at the Zhejiang Chinese Medical University, Hangzhou, China. Moreover, he is visiting professor at the Zhejiang University of Science and Technology, Hangzhou, China.

Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates
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Beating Colon Cancer with Artemisinin

Prior to moving to Adelaide in 2007, Prof Adelson worked at Texas A&M University from 2001, and before that worked for CSIRO from 1988. Dave obtained his PhD in Biomedical Sciences (Biochemistry), from the John A Burns School of Medicine at the University of Hawaii at Manoa in 1985 and carried out postdoctoral research at Duke University.

Product Name Index|J&K Scientific, key element for …

Professor Shilin, Chen, the Director of the Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, now also works as the Director of the World Health Organization Collaborating Center for Traditional Medicine, Academician of International Academy of Sciences for Europe and Asia, Vice President of the Consortium for Globalization of Chinese Medicine, Visiting Professor of Tokyo University of Pharmacy and Life Sciences, Team Leader of Changjiang Scholars and Innovation Team, Ministry of Education (MOE), He has written some related works, including Standard DNA barcodes of Chinese Materia Medica in Chinese Pharmacopoeia.. Prof. Chen has proclaimed that the elucidation of the G. lucidum genome made the organism a potential model system for the study of secondary metabolic pathways and their regulation in medicinal fungi. He has so far published totally more than 400 academic works on famous academic journals, such as Nature Commun, Plant J and PNAS. His academic works have been cited more than 10,000

Natural Products - Compound Libraries

Iron complexes useful in the practice of the invention generally include pharmaceutically acceptable complexes comprising iron, such as, for example, ferrocholinate, ferroglycine sulfate, dextran iron complex, peptonized iron, iron sorbitex, ferric oxide and saccharated iron, as well as iron complexed with iron binding proteins and glycoproteins, such as the holoferritins and holotransferrins.

The concentrations of the endoperoxide compounds in the formulations to be applied in the practice of the present invention will generally range up to the maximally tolerated dosage, but the concentrations are not critical and may vary widely.