ChemInform Abstract: Biosynthesis and Chemical …

Alkaloids are traditionally defined as basic (alkali‐like), nitrogen‐containing organic constituents that occur mainly in plants. The nitrogen in the alkaloid molecule is derived from amino acid metabolism. Since the amino acid skeleton is often largely retained in the alkaloid structure, alkaloids originating from the same amino acid show similar structural features and can be classified according to their biosynthetic origin. The biosynthesis of alkaloids often follows complex pathways and includes stereospecific steps. Alkaloids often have pronounced bioactivities and are therefore thought to play an important role in the interaction of plants with their environment. Alkaloids and extracts of alkaloid‐containing plants have been used throughout human history as remedies, poisons and psychoactive drugs.

ChemInform Abstract: Chemical Structure, Biosynthesis …

ChemInform Abstract: Chemical Structure, Biosynthesis…

Biosynthesis and Chemical Synthesis of …

Alkaloids are defined as basic compounds derived from amino acids, often with heterocyclically bound nitrogen. Pseudoalkaloids are nitrogen‐containing natural products that do not arise from an amino acid core and acquire their nitrogen by transamination of a precursor derived from other biosynthetic pathways.

Biosynthesis of Cylindrospermopsin - American Chemical …

AB - The prodiginine family of bacterial alkaloids is a diverse set of heterocyclic natural products that have likely been known to man since antiquity. In more recent times, these alkaloids have been discovered to span a wide range of chemical structures that possess a number of interesting biological activities. This review provides a comprehensive overview of research undertaken toward the isolation and structural elucidation of the prodiginine family of natural products. Additionally, research toward chemical synthesis of the prodiginine alkaloids over the last several decades is extensively reviewed. Finally, the current, evidence-based understanding of the various biosynthetic pathways employed by bacteria to produce prodiginine alkaloids is summarized.

20/05/2015 · ChemInform Abstract: The Chemical Synthesis of Porphobilinogen: An Important Intermediate in the Biosynthesis of the “Pigments of Life”
Indole Alkaloids of the Stigonematales (Cyanophyta): Chemical Diversity, Biosynthesis and Biological Activity

New insights into the biosynthesis of fosfazinomycin

AB - The development of reliable, eco-friendly processes for the synthesis of nanomaterials is an important aspect of nanotechnology today. One approach that shows immense potential is based on the biosynthesis of nanoparticles using biological micro-organisms such as bacteria. In this laboratory, we have concentrated on the use of fungi in the intracellular production of metal nanoparticles. As part of our investigation, we have observed that aqueous silver ions when exposed to the fungus Fusarium oxysporum are reduced in solution, thereby leading to the formation of an extremely stable silver hydrosol. The silver nanoparticles are in the range of 5-15 nm in dimensions and are stabilized in solution by proteins secreted by the fungus. It is believed that the reduction of the metal ions occurs by an enzymatic process, thus creating the possibility of developing a rational, fungal-based method for the synthesis of nanomaterials over a range of chemical compositions, which is currently not possible by other microbe-based methods.

Cite this article: . Biosynthesis of Lipid by Mortierella Isabellina Grown on Hexadecanol[J]. Chemical Journal of Chinese Universities, 2000, 21(7): 1108-1109.

Department of Chemistry and Chemical Biology

We are pleased to announce that Terpnet 2017, the 13th International Meeting on Biosynthesis, Function and Synthetic Biology, will take place on July 16-20, 2017 in Dalian, Liaoning Province, China.

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Kutchan TM (2005) A role for intra‐ and intercellular translocation in natural product biosynthesis. Current Opinion in Plant Biology 8: 292–300.