Renal cytochrome P-450 induction varies in different species.
The active site of cytochrome P450 contains a heme-iron center
In the male rat kidney, studies with perdeutero-DBCP indicate that DBCP is not metabolized by cytochrome P-450, but presumably by glutathione S-transferase.
Cytochrome P450 - an overview | ScienceDirect Topics
1,2-Dibromoethane and DBCP are metabolized in the liver by both cytochrome P-450 oxidative dehalogenation and by glutathione- S-transferase-mediated substitution.
Enzymes of the cytochrome P450 (CYP) ..
This variability of cytochrome P450 enzymes is seen in the variability of people's ability to detoxify the carcinogens found in cigarette smoke and helps to explain why some people can smoke with only modest damage to their lungs, while others develop lung cancer after only a few decades of smoking.
CYTOCHROME P-450 3A4: Regulation and Role in ..
A considerable amount of research has found that various substances activate cytochrome P450 while others inhibit it.
Good picture of Phase I activities: Good picture of Phase I enzymes:
Cytochrome P450 1A2 (CYP1A2) ..
Cytochrome P-450 mixed-function oxidase activities have been shown immuno-histochemically to be localized in the proximal tubule, particularly in the S2 and S3 segments in the Table 4.
Cytochrome P450 enzymes in drug metabolism: Regulation …
The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.