Properties and synthetic applications of enzymes in organic solvents.
Enzymatic synthesis of Leu- and Met-enkephalin.
Additionally, similar to the incorporation of transition-metal complexes within supramolecular host-guest complexes, the use of artificial metalloenzymes enables the catalytic activity of transition-metal catalysts in biological environments, allowing synthetic catalysts to work collaboratively with other enzymes.
Enzymatic synthesis of aspartame.
This method sets the stage for the generation of artificial enzymes from innumerable combinations of PIX—proteins scaffolds and unnatural metal cofactors for various abiological transformations.
Ronald Breslow is Professor of Chemistry at Columbia University
Use of protected substrates in oligopeptide synthesis has led to a loss of continuity in the reaction sequence and a reduction in yield and productivity, limiting the usefulness of enzymes for such purpose.
Artificial gene synthesis - Wikipedia
Protease CLEAs are promising for peptide synthesis even though autoproteolysis can play a role in this case because of the close proximity and flexibility of the enzyme molecules.
mismatch binding enzymes of the mutS family ..
A 425 fold increase in enzyme activity was observed by the addition of 18-crown-6 to chymotrypsin in the synthesis of a dipeptide in acetonitrile medium (
Artificial Enzymes | Sigma-Aldrich
An interesting approach was designed for the enzymatic synthesis of the cholescystokinin C-terminal octapeptide (CCK-8), which is a biologically active peptide of therapeutic value as an agent for the control of gastrointestinal function (