Antibiotics - Synthesis of Best-Seller Drugs - Chapter 30
Synthesis of Antibiotics | BCA Chemistry
Figure 2. A) Sites of action of inhibitors of bacterial protein synthesis. B) Macrolide antibiotics share a common macrocyclic lactone ring structure & deoxy sugar residues. The structures for erythromycin & clarithromycin differ only at one position (circled in green). Structures reproduced from .
Inhibition of Protein Synthesis by Antibiotics | Sigma …
mechanism, examples not producing an antisense RNA that is complementary to a mRNA, altering porins in the outer membrane of gram-negative cell walls result, producing an altered 30S or 50S ribosomal subunit to which antibiotic no longer binds example
List of antibiotics - Wikipedia
mechanism altering the membranes and transport systems to prevent the entry of the antibiotic into the bacterium and/or ausing an efflux pump to transport the antibiotic out of the bacterium, action blocks active transport, enhancing the function of RNA polymerase leads to, enzymatically adding new chemical groups to aminoglycosides action, mRNA continues to be translated into enzyme leads to increased synthesis of the limited enzyme, Gene products enable the bacterium to become resistant to an antibiotic or chemical agent.
The following is a list of antibiotics
Aminoglycosides are rapidly bactericidal antibiotics which inhibit protein synthesis. These agents mainly interfere with proofreading process. Aminoglycosides are the only bactericidal class among protein synthesis inhibitors.