The control of amylose synthesis - ResearchGate
The requirements for and regulation of the synthesis of amylose
In order to synthesize the amylose-PTHF in the vine-twining polymerization, we designed G7-PTHF as the primer-guest conjugate, and accordingly, synthesized it from G7-N3 and acetylene-terminated PTHF by copper(I)-catalyzed azide-alkyne cycloaddition, click chemistry (); the former was prepared by the literature procedure and the latter was obtained by ring-opening polymerization of tetrahydrofuran by using MeOTf, followed by treatment with sodium propargyl alkoxide. The 1H NMR spectrum of the product in DMSO-6 fully supported the structure of G7-PTHF ().
Improved understanding of rice amylose biosynthesis …
We recently achieved to synthesize a novel supramolecular polymer, which was composed of continuum of the amylose-poly(L-lactide) (PLLA) inclusion complexes, was produced when a G7-functionalyzed PLLA was used as a primer-guest conjugate substrate in the vine-twining polymerization. In this approach, a propagating amylose chain started from G7 moiety in the primer-guest conjugate by the phosphorylase catalysis includes a polyester, PLLA, segment in the other substrate. Such special type of the vine-twining polymerization among the substrates successively takes place, giving rise to the novel inclusion supramolecular polymer composed of amylose and PLLA. This vine-twining polymerization approach for the supramolecular polymer has inspired us to be applicable to other hydrophobic polymers. Because it was found to form the inclusion complex with amylose, in this paper, we employed a polyether, poly(tetrahydrofuran) (PTHF), and demonstrated the synthesis of inclusion supramolecular polymer composed of amylose and PTHF (amylose-PTHF) by means of the vine-twining polymerization using G7-functionalized PTHF (G7-PTHF) as a primer-guest conjugate.