Synthesis description for preparation of 8-HYDROXYQUINOLINE

AB - New aryl substituted 8-hydroxyquinoline derivatives have been synthesized. The compounds were characterized by 1H, 13C-NMR spectroscopy and mass spectrometry. The aluminum complexes of these derivatives show strong green emission in the range 530-535 nm with high quantum yield compared to the parent tris (8-hydroxyquinolinato)aluminum(III) complex. The structure of the aryl-substituted 8-hydroxyquinoline aluminum complexes in the ground state have been optimized at the B3LYP/6-31G (*) level of theory. The parent 8-hydroxyquinoline has also been examined using this method with the same basis set. A clear correlation between the shortening of the Al-N bond and red shift in the fluorescence emission band was observed. We have also found that substitution at the 5 and 7 position of the 8-hydroxyquinoline ligand cause simultaneous energy lowering of both highest occupied molecular orbital and the lowest unoccupied molecular orbital with the 5, 7-aryl substituted derivatives exhibiting the greatest effect.

Synthesis of 8 -Hydroxyquinoline ..

T1 - Design and synthesis of 8-hydroxyquinoline-based radioprotective agents

Synthesis of 8-Hydroxyquinoline Derivatives as Novel Antitumor ..

Studies of structural, chemical and synthetic aspects of 8-hydroxyquinoline (8-HQ) and its derivatives are reviewed. A special emphasis is given to applications of recently developed 8-HQ derivatives in various fields such as OLEDs, , , and insecticidal agents.

First Safe and Practical Synthesis of 2-Amino-8-hydroxyquinoline.

New aryl substituted 8-hydroxyquinoline derivatives have been synthesized. The compounds were characterized by 1H, 13C-NMR spectroscopy and mass spectrometry. The aluminum complexes of these derivatives show strong green emission in the range 530-535 nm with high quantum yield compared to the parent tris (8-hydroxyquinolinato)aluminum(III) complex. The structure of the aryl-substituted 8-hydroxyquinoline aluminum complexes in the ground state have been optimized at the B3LYP/6-31G (*) level of theory. The parent 8-hydroxyquinoline has also been examined using this method with the same basis set. A clear correlation between the shortening of the Al-N bond and red shift in the fluorescence emission band was observed. We have also found that substitution at the 5 and 7 position of the 8-hydroxyquinoline ligand cause simultaneous energy lowering of both highest occupied molecular orbital and the lowest unoccupied molecular orbital with the 5, 7-aryl substituted derivatives exhibiting the greatest effect.

Step B: Synthesis of tamarind 8-hydroxyquinoline-5-sulfonic acid (THQSA) resin
Scheme1: Synthesis of tamarind 8-hydroxyquinoline-5-sulfonic acid (THQSA) resin

SYNTHESIS OF NOVEL TAMARIND 8-HYDROXYQUINOLINE …

Finally, it was washed with pure methanol. The product tamarind 8-hydroxyquinoline-5-sulfonic acid (THQSA) resin was a free-flowing light yellow powder and the yield was 208.5 g. The reaction scheme is shown in step B of Scheme1.

Synthesis of Mannich Bases of 8-Hydroxyquinoline ..

Epoxypropyl ether of tamarind, synthesized in Step A was allowed to react with 22.52 g (0.1 mol) of 8-hydroxyquinoline-5-sulfonic acid. The mixture was stirred for 4 h at 60°C and left overnight. The product was filtered under vacuum and washed with 90% methanol containing a few drops of hydrochloric acid to remove inorganic impurities.

Quinoline synthesis - Organic chemistry

Methods: THQSA resin was synthesized by reacting epoxy propyl ether of tamarind with 8-hydroxyquinoline-5-sulfonic acid. The epoxy propyl ether of tamarind was synthesized by the reaction of epoxy chloropropane (epichlorohydrin) with tamarind kernel powder (TKP). The characterisation of the THQSA resin was carried out by FTIR (Fourier transform Infrared) spectra, elemental analysis and total ion exchange capacity. The effects of pH, treatment time, treatment temperature, resin quantity and flow rate on the removal of metal ions from industrial effluent were also studied.