Hazard Statements: H315-H319-H335

Deng, S.; Zhao, P.; Dai, Y.; Huang, B.; Hu, A. Synthesis of soluble conjugated polymeric nanoparticles through heterogeneous Suzuki coupling reaction. Polymer 2015, 64, 216-220.Im, Y.; Song, W.; Lee, J. Y. Effect of the molecular structure of the host materials on the lifetime of green thermally activated delayed fluorescent organic light-emitting diodes. J. Mater. Chem. C 2015, 3 (31), 8061-8065.

2-Pyrrolidinone, 1-(2-hydroxyethyl)(3445-11-2)

 Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Saturated atmosphere: 167 980 mg/m3 (37 000 ppm) at 25 °C.

Single, oral doses of 0, 1, 5, 25, 50, or 100 mg 1,3- dichloropropene 97% ( cis-62% and trans-isomer 38%) were given for NPS studies and 0, 1, 50, or 100 mg 14C-1,3-dichloropropene/kg body weight for binding studies.

Explosive limit: 195 220 mg/m3 (43 000 ppm) (80 °C).

EFFECTS ON ORGANISMS IN THE ENVIRONMENT The United States Environmental Protection Agency published a Health and Environmental Effects Profile for 1,3-Dichloropropene in 1985 (US EPA, 1985).


Estra-1,3,5(10)-triene-3,17-diol (17β)-

Acute toxicity of 1,3-dichloropropene for non-target aquatic crustacea Species Temperature 48-h LC50 96-h LC50 Reference (°C) (mg/litre) (mg/litre) Water flea 21 0.090a - Mayer & (Daphnia magna) Ellersieck (1986) Mysid shrimp - 0.79 US EPA (1980); (Mysidopsis bahia) Leblanc (1984) a 48-h EC50 6 mg/litre (US EPA, 1980; Leblanc, 1980) in a static system.

"MIX D/D" at levels up to 145 mg/m3 does not cause any toxic effects.

Single oral doses of 0, 1, 5, 25, 50, or 100 mg 1,3-dichloropropene 97% ( cis- 62% : trans-isomer 38%)/kg body weight were given for NPS studies and 0, 1, 50, or 100 mg 14C-1,3- dichloropropene/kg body weight for binding studies.

Cholan-24-oic acid, 3,12-dihydroxy-, (3α,5β,12α)-

Acute toxicity of cis- and/or trans-1,3-dichloropropenes in Daphnia magna Substance Age System Temperature 48-h EC50 Reference (°C) (mg/litre) Cis-1,3 DCP 24 h statica 18-22 1.4 Girling (1989a) (96%) Trans-1,3 DCP 24 h staticb 18-22 3.1 Girling (1989c) (95.4% trans + 0.3% cis) Cis- + trans- 24 h staticc 18-23 3.1 Girling (1989b) mixture (51-52% cis + 44% trans) a pH 7.6-8.4; total hardness 176 mg/litre; dissolved oxygen 8.8-9.8 mg/litre.

With TA98 and TA1537, positive and negative effects were found.

Reduction in Compound Fungi Bacteria and actinomycetes Cis-1,3-dichloropropene 85-95% reduction 85-100% reduction at 25 mg/kg soil at 250 mg/kg soil Trans-1,3-dichloropropene 100% reduction 100% reduction at at 250 mg/kg soil 1000 mg/kg soil 7.1.2 Algae The 96-h EC50 value for growth, based on the concentration of chlorophyll a and also on cell numbers of the freshwater green algae Selenastrum capricornutum in a static system, was 4.95 mg/litre for 1,3-dichloropropene.

(1983) TA98, TA1537 3-333 µg/ml plate S9 mix/none - Haworth et al.

6.4.2 Rat Groups of 3-9 male Fischer 344 rats (200-260 g) were administered 50 mg cis-1,3-dichloropropene (94.1% cis- and 2.5% trans-) or 50 mg trans-1,3-dichloropropene (97.3% trans- and 0.8 cis-)/kg body weight, by gavage.

The density is 1.1595 g/ml at 20 °C, and 1.437 g/ml at 25 °C.

The EC50 (percentage reduction in mean specific growth rate), (24-48 h) and EC50 (24-72 h) values determined by analysis of average specific growth rates were: cis- isomer 4.6 and 3.1 mg/litre; trans-isomer 6.6 and 7.5 mg/litre; and, for the mixture, 11 and 3.6 mg/litre, respectively (Girling, 1989a,b,c).